Clinical efficacy and complications of transoral endoscopic peroral endoscopic myotomy for achalasia
10.3969/j.issn.1007-1989.2016.07.007
- VernacularTitle:经口内镜下肌切开术治疗贲门失弛缓症临床疗效和并发症的分析
- Author:
Bin ZENG
;
Guangsheng HU
;
Weiwei ZHOU
;
Liang CHEN
;
Yong DAI
;
Aijun LIAO
- Keywords:
achalasia;
peroral endoscopic myotomy;
curative effect;
complications
- From:
China Journal of Endoscopy
2016;22(7):26-30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficacy and complications of transoral endoscopic peroral endo﹣scopic myotomy (POEM) for achalasia (AC). Methods 38 patients with AC received POEM treatment from January 2013 to January 2013 in our digestive endoscopy center. Procedure-related complications and gastroesophageal re﹣flux were observed, and ECKARDT score and the lower esophageal sphincter pressure changes were analysed. Results All patients underwent POEM successfully. No serious POEM-related complications were observed, bleed﹣ing, gas related complications were treated successfully by conservative treatment. Postoperative follow-up time was 10.4 months (range 9 to 12 months), the symptoms of all the patients were alleviated, ECKARDT score average from preoperative 8.7 points dropped to postoperative 1.2 points (P<0.01), esophageal sphincter pressure decreased sig﹣nificantly, mean pressure dropped from preoperative (33.40 ± 11.80) mmHg to postoperative (13.50 ± 4.30) mmHg (P< 0.01) and gas related complications occurred in 6 cases (15.78 %), esophageal reflux occurred rate total was 23.68%(9/38). Conclusion POEM is safe and effective for the treatment of AC, and has better long-term effect.
