Clinical Study on Xuebijing Injection Combined with Antibiotics in the Prevention of Systemic Inflammatory Response Syndrome after Ureteroscopy
- VernacularTitle:血必净联合抗菌药预防输尿管镜碎石术后全身炎症反应综合征临床观察
- Author:
Wei WANG
;
Huayu WEI
;
Hai YU
;
Mei LU
;
Bin HU
;
Jiangbo LIANG
;
Zhixiang LAN
- Keywords:
Xuebijing;
Systemic inflammatory response syndrome;
Ureteroscopy;
Sepsis
- From:
China Pharmacist
2017;20(8):1393-1395
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To assess the clinical efficacy of Xuebijing injection in the prevention of postoperative systemic inflammatory response syndrome (SIRS) in the patients with ureteral stones and urinary tract infection during the perioperative period of ureteroscopy.Methods: Totally 64 cases with ureteral stones complicated with urinary tract infection treated with ureteroscopy were selected as the subjects and divided into two groups according to the digital method.The 32 cases in the control group were given the conventional antibiotics during the perioperative period for preventing the incidence of SIRS, and the observation group was given 500ml Xuebijing added to 100ml normal saline for intravenous drip additionally.The incidence of SIRS and the laboratory indicators after the operation were observed and compared between the groups.Results: The incidence of postoperative SIRS of the observation group was 9.38% , which was lower than that of the control group (34.38% , P <0.05);the incidence of sepsis of the observation group was 0%, while there was no statisticcally difference bettween the two groups(P＞0.05).The C-reactive protein (CRP), procalcitonin (PCT), leucocyte count and endotoxin in the observation group on the 2nd, 4th and 6th day after the operation were better than those in the control group, and the difference was statistically significant (P＜0.05).Conclusion: Xuebijing injection combined with antibiotics has significant clinical effect on the incidence of SIRS after ureteroscopy in the patients with ureteral stones and urinary tract infection, which can effectively improve the clinical indicators and reduce the incidence of sepsis, and is worthy of clinical promoted application.
