Study on the General Pharmacology of Potentill Discolor Bung
- VernacularTitle:翻白草的一般药理学研究
- Author:
Jiaju YAN
;
Haifeng SUN
;
Ping YAN
;
Weitong YAN
- Keywords:
Potentill;
General pharmacology;
Cardiovascular system;
Respiratory system
- From:
China Pharmacist
2017;20(8):1466-1468
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of potentill on all systems of experimental animals to provide experimental evidence for the comprehensive safety evaluation of potentill.Methods: Mice and rats were given potentill orally to determine the influence on all systems, and the general pharmacological activities of potentill were recorded.Results: The general behavior of mice was normal after the adminisration of potentill , the test samples showed no synergetic hypnotic effect with nembutal at subthreshold dose, and had no influence on the spontaneous activity and body coordination ability of mice (P＞0.05).The test samples showed no obvious influence on the cardiovascular system and respiratory system of rats (P＞0.05).Conclusion: Potentill meets the general requirements of pharmacology at the prescribed dose.
