Application of Mifepristone in One Case of Cushing's Syndrome and Review of Related Guidelines
- VernacularTitle:米非司酮在库欣综合征中的应用1例及相关指南复习
- Author:
Jingna LI
;
Zhu ZHU
;
Yan TANG
- Keywords:
Mifepristone;
Cushing's syndrome;
Diabetes;
Hypokalemia
- From:
China Pharmacist
2017;20(8):1439-1442
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the efficacy of mifepristone in patients with Cushing's syndrome and the incidence of adverse reactions to provide basis for its clinical use.Methods: One case of Cushing's syndrome treated with mifepristone participated by pharmacist was analyzed.Results: Mifepristone could significantly improve hyperlipidemia and the complications of the patient, meanwhile, the risk of hypoglycemia should be paid attention and insulin therapy should be withdrawn timely.Conclusion: Mifepristone can significantly reduce blood glucose levels and improve the appearance of Cushing.At the same time, the level of serum potassium needs close monitoring to avoid the occurrence of hypokalemia.
