Review of national external quality assessment for neonatal screening laboratory in Xinjiang for 7 years
10.3969/j.issn.1673-4130.2017.13.002
- VernacularTitle:新疆地区参加全国新生儿疾病筛查实验室室间质评7年回顾
- Author:
Hui ZHANG
;
Yongfang TIAN
;
Changmin WANG
;
Jianyong LIU
;
Qifeng LI
;
Weidong WU
- Keywords:
neonatal screening;
external quality assessment;
phenylalanine;
thyrotropin
- From:
International Journal of Laboratory Medicine
2017;38(13):1732-1734,1737
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review the phenylalanine(Phe) and thyrotropin(TSH) results of national external quality assessment(EQA)in neonatal screening laboratory for 7 years,evaluate qualitity control level and summarize the problems in the screening measurement.Methods The Phe and TSH values in dried blood spot specimens on filter paper distributed by national center for clinical laboratory were measured by fluorometrie method and time-resolved fluorescence immunoassay respectively.The Phe and TSH EQA results from 2010 to 2016 year were analyzed.Results Five specimens were distributed by EQA organizer each time,and 3 times each year.(1) In the 105 specimens of 21 batches,the bias ranges of Phe and TSH measurement were wide and their average values were 2.21% and 0.98% respectively.(2) Quantitative results analysis :Six quantitative results of Phe measurement and two quantitative results of TSH measurement were out of aunty control(bias ≥30% or ≤-30%),accounting for 5.71%(6/105)and 1.9%(2/105) respectively.(3)Qualitative results analysis:The Phe and TSH qualitative analysis of specimens conformed to the expected results(100%).The result of every batch was up to 80%.Conclusion It is useful to evaluate the measurement competence,find out the problems in the Phe and TSH measurement in neonatal screening laboratory and resolve them in time.Consequently,it is useful to improve the quality of measurement,reduce the error and ensure the accuracy of results.
