The level of platelet leukocyte aggregates in patients with acute cerebral infarction and their short term prognosis
10.3969/j.issn.1673-4130.2017.13.004
- VernacularTitle:血小板-白细胞聚集体在急性脑梗死患者及其短期预后的水平变化
- Author:
Feng GAO
;
Ruifang LIU
;
Xiaolin YAN
;
Hongjie ZHANG
;
Haiying QI
;
Qi LIU
;
Xiaojun ZHANG
- Keywords:
platelet-leukocyte aggregates;
acute cerebral infarction;
short-term prognosis
- From:
International Journal of Laboratory Medicine
2017;38(13):1738-1739,1742
- CountryChina
- Language:Chinese
-
Abstract:
Objective to investigate the level of platelet leukocyte aggregates in patients with acute cerebral infarction and their short term prognosis.Methods 105 patients with acute cerebral infarction onset within 24 hours were selected continuously,then platelet leukocyte aggregates including neutrophil aggregates (PNA) and platelet monocyte aggregates (PMA) and platelet lymphocyte aggregates (PlyA) were detected by flow cytometry within 24 hours of admission and the incidence of 14 days.modified Rankin Scale(mRS) was performed at 14 days of onset,as a prognostic indicator,and the mRS score was good at 3.The score >3 mRS was divided into poor prognosis.The level of platelet leukocyte aggregates was detected in 50 healthy subjects.Results (1) The platelet leukocyte aggregates in patients with acute cerebral infarction group were significantly higher than that of the healthy group,which was statistically significant (P<0.05).(2)MRs score <3 group and mRS score >3 score comparison,the difference of white blood cell aggregates was statistically significant(P<0.05).Conclusion leukocyte aggregates could be used as an index of short-term prognosis in patients with acute cerebral infarction.
