Diagnostic value of combination of VCA-IgA and multilayer enhanced spiral CT in the diagnosis of nasopharyngeal carcinoma
10.3969/j.issn.1673-4130.2017.13.010
- VernacularTitle:血清VCA-IgA检测联合螺旋CT增强扫描在鼻咽癌诊断中的应用
- Author:
Tianxing JI
;
Linqiang ZHU
;
Zhaoen MA
;
Bo CHEN
;
Qiang ZHOU
- Keywords:
multilayer Spiral CT;
VCA-IgA;
nasopharyngeal carcinoma;
diagnosis
- From:
International Journal of Laboratory Medicine
2017;38(13):1754-1755,1758
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of VCA-IgA and multilayer enhanced spiral CT(MESCT) in the diagnosis of nasopharyngeal carcinoma.Methods Retrospective analysed the data on serum VCA-IgA test and MESCT of 385 patients with suspected nasopharyngeal disease,and the results were confirmed by surgery and pathology.Comparatively analysed the two methods in differential diagnosis of nasopharyngeal carcinoma and benign diseases.Finally,calculated the sensivity,speficity,positive predictive value,negative predictive value and accuracy in diagnosis of nasopharyngeal carcinoma.Results The positive rate of serum VCA-IgA,MESCT and combination of those two methods in naospharyngeal carcinoma were significantly higher than those in nasopharyngeal benign disease(P<0.05);combination of the methods significantly improve the sensitivity and accuracy in diagnosis of nasopharyngeal carcinoma,the specificity was lower than VCA-IgA,higher than MESCT alone.Conclusion Combination of serum VCA-IgA and MESCT were excellent strategy for diagnosis of nasopharyngeal carcinoma.
