Analysis of rapid detection of Treponema pallidum antibody before voluntary blood donation and strategy optimization
10.3969/j.issn.1673-4130.2017.13.021
- VernacularTitle:无偿献血者献血前梅毒螺旋体抗体快速检测结果分析及策略优化
- Author:
Xiancheng CAI
;
Qing YE
;
Fangfei LIU
;
Zhilin HONG
- Keywords:
pre-donation screening;
Syphilis antibody;
fast detection;
strategy optimization
- From:
International Journal of Laboratory Medicine
2017;38(13):1784-1785,1789
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the performance of fast Treponema pallidum(TP) detection in voluntary blood donors and optimize the strategy for pre-donation screening.Methods Before blood donation,the gold standard TP test strip was used to make a fast detection.After blood donation,the TP-ELISA was used to test the blood.Then,analyze the donors′ anti-TP positive rate,times and intervals of donating,false positive and negative of TP fast detection.Results From 2014 to 2015,among 73 990 donors who were tested by using fast TP detection,0.71% of them(529 donors) were positive.Among the positive donors,89.2% of them(472 donors) were first-time blood donors.35 donors′ donating intervals were more than 3 years,who accounted for 61.4% of the donors who had donated for more than once.The numbers of the false positive obtained from fast TP detection were 5 and the false negative was 15.By applying the fast TP detection before blood donation,the rate of anti-TP positive had been declined from 0.71% to 0.17%.Conclusion The rejection rate of TP positive can be significantly reduced by using fast TP detection before blood donation.The fast TP detection can be used to optimize the pre-donation screening and promote blood donation service efficiency and level,while donating times and intervals of the blood donors were also considered.
