Notch signaling pathway and bronchiolitis
10.3760/cma.j.issn.1673-4408.2017.06.001
- VernacularTitle:Notch信号通路与毛细支气管炎的相关性研究进展
- Author:
Liangxiao LIU
- Keywords:
Bronchiolitis;
Notch signaling pathway;
Respiratory syncytial virus
- From:
International Journal of Pediatrics
2017;44(6):369-372
- CountryChina
- Language:Chinese
-
Abstract:
Bronchiolitis is the most common lower respiratory tract infection in infancy and early childhood.The main pathogen is respiratory syncytial virus (RSV),which is one of the main factors in hospitalized infants,closely related to asthma.However,the detailed mechanism is not clarified,and there is no specific treatment.Recent studies have showed that Notch signaling pathway plays an important role in its pathogenesis.This review mainly summarizes the association between bronchiolitis immunological mechanisms and Notch siganling pathway.
