Ultrasound-guided percutaneous transhepatic thrombolysis for treatment of portal vein thrombosis after liver transplantation
10.3760/cma.j.issn.1008-1372.2017.06.007
- VernacularTitle:超声引导下经皮经肝门静脉穿刺辅助溶栓治疗肝移植术后门静脉血栓
- Author:
Jia LUO
;
Jianwei LIN
;
Liya SU
;
Manxia LIN
;
Wenzhe FAN
;
Xiaoyan XIE
;
Wenshuo TIAN
- Keywords:
Ultrasonography;
Portal vein/SU;
Hepatic veins/SU;
Phlebotomy;
Thrombolytic therapy;
Venous thromboembolism/CO/SU;
Liver transplantation/AE
- From:
Journal of Chinese Physician
2017;19(6):821-823
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effective and safety of ultrasound-guided percutaneous portal vein guide wire placement adjunct to thrombolytic catheter,which treating portal vein thrombosis after liver transplantation.Methods From Jan 2012 to Dec 2015,a total of 6 patients (5 male,1 female,average age 50.6 years old,age range 41-65 years old) with portal vein thrombosis after liver transplantation were retrospectively studied.The diagnosis was confirmed by contrast enhanced ultrasound (CEUS) with hypoechonic and no enhancement in portal vein.With ultrasound-guided a 18-guage guide wire was placed in right branch of portal vein,and a guidewire was placement.After exchanging the catheter,the thrombosis was confirmed again by venography.A thrombolytic catheter was placed and local thrombolysis therapy was performed.Results The guidewires were successfully placed in 6 patients.The thrombolytic catheters were successfully placed in 5 patients (day 2-60 after operation),and failed in 1 patient (9 years after operation).With 5-11 days urokinase injection,the patency of portal vein was found in 5 patients,of which 4 patients was treated by angioplasty and stent placement.With 16-31 months follow-up,the patency of portal vein was maintained.Neither server complication nor related-death was occurred.Conclusions Ultrasound-guided percutaneous portal vein guide wire placement adjuncts thrombolytic catheter is effective and safety for treating portal vein thrombosis after liver transplantation.