Exosomal microRNAs and their roles in tumors
10.3760/cma.j.issn.1673-422X.2017.06.009
- VernacularTitle:外泌体装载的微小RNA及其在肿瘤中的作用
- Author:
Dongwei ZHU
;
Yungang WANG
;
Xueli XIA
;
Shengjun WANG
- Keywords:
Neoplasms;
MicroRNAs;
Exosomes
- From:
Journal of International Oncology
2017;44(6):438-441
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes contain many components including variety kinds of lipids,proteins,microRNAs (miRNAs) and so on.They can transport their loaded substances to the recipient cells and play a role of biology.Exosomal miRNAs play important roles in the occurrence and development of tumors,and they are closely related to the tumor growth,metastasis,drug resistance and immune regulation.Exosomes and exosomal miRNAs can be served as reference indexes for tumor metastasis and prognosis,which provide new targets for tumor therapy.
