Research progress of Dickkopf-1 related tumor metastasis
10.3760/cma.j.issn.1673-422X.2017.06.010
- VernacularTitle:Dickkopf-1相关肿瘤转移研究进展
- Author:
Qiumei ZHU
;
Yong ZHANG
- Keywords:
Neoplasm metastasis;
Therapy;
Dickkopf-1
- From:
Journal of International Oncology
2017;44(6):442-444
- CountryChina
- Language:Chinese
-
Abstract:
As a secreted glycoprotein,Dickkopf-1 (DKK1) is closely related to tumor metastasis,and it is highly or lowly expressed in tumor.The high expression of DKK1 promotes the metastasis of a variety of malignant tumors including liver cancer,gastric cancer,non-small cell lung cancer and breast cancer.Recent studies have found that DKK1 is inextricably bound up with the latent metastasis of tumor.
