Research progress of the patrolling monocytes in tumor
10.3760/cma.j.issn.1673-422X.2017.05.010
- VernacularTitle:巡逻单核细胞在肿瘤中的研究进展
- Author:
Ping FANG
;
Ke XU
;
Bin CHEN
;
Hong GAO
;
Yanwei ZHU
- Keywords:
Neoplasms;
Immune;
Monocytes
- From:
Journal of International Oncology
2017;44(5):366-368
- CountryChina
- Language:Chinese
-
Abstract:
Patrolling monocyte (PMo) is a subset of monocytes.Its main function is patrolling vascular endothelium and removing cellular debris from the microvasculature.Studies have revealed that PMo can inhibit the growth of tumor cells,recruiting NK cells to kill tumor cells.PMo can prevent tumor cells metastasis to the lung,which plays a role of immunosurveillance.PMo may be a target for cancer immunotherapy.
