The mechanism of MLN4924 for anticancer therapy
10.3760/cma.j.issn.1673-422X.2017.05.012
- VernacularTitle:MLN4924抗肿瘤作用机制
- Author:
Mi YANG
;
Hongren CEN
;
Cheng LONG
;
Jiejun FU
- Keywords:
Neoplasms;
MLN4924
- From:
Journal of International Oncology
2017;44(5):373-375
- CountryChina
- Language:Chinese
-
Abstract:
MLN4924 can inhibit the proliferation,invasion and metastasis of tumor by inducing tumor cells apoptosis,senescence and autophagy,which can inhibit tumor angiogenesis and enhance the sensitivity of radiotherapy and chemotherapy.Therefore,MLN4924 plays a good anti-tumor effect.
