Research and application of NVP-BEZ235 in lung cancer
10.3760/cma.j.issn.1673-422X.2017.05.015
- VernacularTitle:NVP-BEZ235在肺癌中的研究及应用进展
- Author:
Xiaoyu CHAI
;
Meng XU
;
Xinmin LIU
- Keywords:
Lung neoplasms;
Mutation;
NVP-BEZ235
- From:
Journal of International Oncology
2017;44(5):383-385
- CountryChina
- Language:Chinese
-
Abstract:
NVP-BEZ235 is a newly developed dual phosphatidyl linositol kinase 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor.Studies have revealed that NVP-BEZ235 combinate with other drugs were effective in the treatment of lung cancer.NVP-BEZ235 might have a potential application value for the treatment of lung cancer of EGFR mutation subtype and KRAS mutation subtype.