Risk factors for acute kidney injury in overweight patients with acute Stanford type A aortic dissection following Sun's pocedure
10.3760/cma.j.issn.1001-4497.2017.05.011
- VernacularTitle:超重急性A型主动脉夹层患者孙氏术后急性肾损伤的危险因素分析
- Author:
Xudong PAN
;
Honglei ZHAO
;
Tao BAI
;
Jinrong XUE
;
Ningning LIU
;
Huanyu QIAO
;
Yongmin LIU
;
Lizhong SUN
- Keywords:
Kidney injury;
Body mass index;
Aortic dissection;
Risk factors;
Sun's procedure
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2017;33(5):295-299
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the risk factors for acute kidney injury (AKI) in overweight patients who underwent surgery for the treatment of acute type A aortic dissection(TAAD).Methods A retrospective study including 108 consecutive overweight patients(body mass index(BMI) ≥24) between January 2010 and May 2013 in Beijing Anzhen Hospital was performed with Sun's procedure of total aortic arch replacement and frozen elephant trunk implantation.AKI was as defined according to Acute Kidney Injury Network (AKIN) criteria based on serum creatinine(sCr) or urine output.Results The mean age of the patients was(43.69 ± 9.66) years.During the postoperative period seventy-two patients(66.7%) developed AKI.The overall postoperative mortality rate was 7.4%,8.3% in AKI group and 5.6% in non-AKI group.There is no statistically significant difference between the two groups(P =0.32).A logistic regression analysis was performed to find out the independent risk factors for AKI:elevated preoperative sCr level and postoperative drainage volume.Renal replacement therapy(RRT) was performed in fifteen patients (13.9 %).Conclusion A higher incidence of AKI (66.7 %) in overweight patients following acute TAAD was identified.The logistic regression model found out elevated preoperative sCr level and 72 hour drainage volume as the two independent risk factors for AKI in overweight patients.More attention should be paid to prevent AKI in overweight patients following TAAD.