Predictive value of donor's glomerular filtration rate to recipient's weight ratio in early clinical outcome in living-related donor transplantation
10.3760/cma.j.issn.0254-1785.2017.03.008
- VernacularTitle:亲属活体供肾肾小球滤过率与受者体重比值对移植肾功能预测的研究
- Author:
Dawei ZHANG
;
Xiang LI
;
Liang XU
;
Qing YUAN
;
Xing WEI
;
Shuxin LI
;
Ming CAI
- Keywords:
Kidney transplantation;
Glomerular filtration rate;
Renal function
- From:
Chinese Journal of Organ Transplantation
2017;38(3):160-164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether the donor's glomerular filtration rate (GFR) to recipient's weight ratio (Dg/Rw) is a useful tool to predict early clinical outcome in living-related do-nor transplantation.Methods A total number of 108 living donor transplant recipients in the Chinese Military 309th Hospital from Jan.2014 to July 2015 were enrolled in this study.The patients who had multi-organ transplantation or developed grafts rejection,delayed graft function,hydronephrosis or renal vascular stenosis were excluded.The 90 qualified recipients were divided into G1 group (Dg/Rw ≤0.81),G2 group (Dg/Rw 0.81～1.11),and G3 group (Dg/Rw≥1.12).We respectively analyzed the relationship between recipient's serum creatinine Scr and Dg/Rw at 3-,7-,30-day and 1 year after transplantation.Results Scr at 3-,7-,30-day and 1 year after transplantation had linear correlation with Dg/Rw.As compared with G1 and G2 groups,Scr level was significantly reduced in G3 group at different time points (P＜0.05).Conclusion Dg/Rw has a negative relationship with Scr level after renal transplantation.Pre-transplant Dg/Rw is a potential index to predict the early clinical outcome in living-related donor transplantation.
