Application of gene-sequencing technique in the monitoring of bacterial infectious diseases
10.3969/J.ISSN.1672-8270.2017.07.035
- VernacularTitle:基因测序技术在细菌性传染病监测中的应用
- Author:
Chun ZHANG
;
Yuanyuan ZHANG
- Keywords:
Gene-sequencing;
Sequencing instrument;
Bacterial infectious diseases;
Genome;
Precision medicine
- From:
China Medical Equipment
2017;14(7):134-138
- CountryChina
- Language:Chinese
-
Abstract:
Gene-sequencing technique is the most important techniques in the research of modern molecular biology. After decades of development, it has been widely used in disease detection and monitoring due to its high throughput, fast speed and high accuracy. Therefore, the principle and development process of gene-sequencing technique were summarized in this paper, and the principle of gene-sequencing technique of the first generation, the second generation and the third generation and all kind of gene-sequencing equipment based on various principle of technique were systematic introduced in this paper. Besides, the paper also explored and discussed the selection and application of various kind of gene-sequencing equipment in the emergency and early warning monitoring for bacterial infectious disease. On the other hand, the paper also summarized and prospected the application and development of gene-sequencing technique in biology and biomedical research.