Observation on the effect of dexmedetomidine on regional cerebral oxygen saturation and postoperative cognitive function in elder patients received prostatectomy by using laparoscope
10.3969/J.ISSN.1672-8270.2017.07.024
- VernacularTitle:老年患者腹腔镜前列腺癌根治术中应用右美托咪定对局部脑氧饱和度及术后认知功能情况的观察
- Author:
Yong WANG
;
Yuanwen ZHANG
- Keywords:
Dexmedetomidine;
Elderly patients;
Regional cerebral oxygen saturation;
Cognitive function;
Laparoscope;
Prostatectomy
- From:
China Medical Equipment
2017;14(7):95-98
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To research the effect of dexmedetomidine on regional cerebral oxygen saturation(rSO2)and postoperative cognitive function in elder patients received prostatectomy by using laparoscope. Methods: 60 elderly patients received prostatectomy by using laparoscope were divided into observation group (30cases) and control group (30cases) as random number table. In observation group, the dexmedetomidine was injected by venous pump after endotracheal intubation of general anesthesia was implemented, while the equivalent normal saline (NS) was injected by venous pump in control group. The rSO2, PaCO2 and PaO2 of different time point between the two groups were observed and compared. The usages of propofol and remifentanil, the situation of postoperative restlessness, and situation of nausea and vomiting between the two groups were compared. Besides, the scores of MoCA of different time point between the two groups also were compared. Results: The usages of propofol and remifentanil of observation group were significantly lower than that of control group (t=3.449, t=9.466, P<0.05), respectively. The occurrence rate of postoperative restlessness and occurrence rate of nausea and vomiting were 10.0% and 6.7%, respectively, while they were 13.3% and 3.3%in control group, and the differences of them between the two groups were no significant (x2=0.162, x2=0.351, P>0.05). The score of MoCA of observation group was significant higher than that of control group (t=8.938, P<0.05) at postoperative 1d. Conclusion: In the elder patients received prostatectomy by using laparoscope, the dexmedetomidine doesn't affect the rSO2 level of patients, while it contributes to fast recover the postoperative cognitive function of patients.
