The intervention effectiveness of moderate aerobic exercise for patients with Alzheimer's disease:a meta-analysis
10.3761/j.issn.0254-1769.2017.06.009
- VernacularTitle:中度有氧运动对阿尔茨海默病患者干预效果的Meta分析
- Author:
Shanshan YANG
;
Xiujuan YANG
;
Min LI
;
Shufang ZOU
- Keywords:
Alzheimer Disease;
Exercise Therapy;
Review Literature as Topic
- From:
Chinese Journal of Nursing
2017;52(6):686-691
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiveness of moderate aerobic exercise intervention for patients with Alzheimer's disease. Methods Randomized Clinical Trials(RCTs) that assessed the effectiveness of aerobic exercise intervention for patients with Alzheimer's disease were reviewed using multiple electronic databases systematically. Data were analyzed by RevMan 5.2.0 version. Results Eight RCTs were included. Meta-analysis indicated that moderate aerobic exercise could improve the score of MMSE(WMD=1.58,95%CI:0.63~2.53,P<0.01),reduce the score of Alzheimer's disease assessment scale-cognitive subscale(ADAS-Cog)(WMD=-4.06,95%CI:-6.83~-1.28,P<0.01) and the score of Neuropsychiatric Inventory(WMD=-3.97,95%CI:-5.69~-2.25,P<0.01). Conclusion Moderate Aer-obic exercise can improve cognitive function of Alzheimer's patients,and improve their neuropsychiatric symptoms.
