Observation on the effect of metformin combined with nutrition and exercise therapy on metabolic syndrome
10.3969/j.issn.1005-1678.2017.07.018
- VernacularTitle:二甲双胍联合营养及运动治疗用于代谢综合征的效果观察
- Author:
Na GUO
- Keywords:
metformin;
nutrition;
exercise;
metabolic syndrome
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(7):52-53,56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of metformin combined with nutrition and exercise therapy on metabolic syndrome.Methods 100 patients treated in our hospitcal from July 2012 to April 2017 were randomly divided into two groups.The control group received metformin treatment.The patients in the experimental group received metformin combined with nutrition and exercise therapy.Blood pressure(BP), TG, LDL-C, HDL-C and WC were measured and compared between the two groups after three months of treatment.The therapeutic effect of the two groups was determined.Results The effective rate was 60.0% in the control group and 80.0% in the experimental group.The difference was statistically significant(x2=9.52, P<0.05).The improvement of metabolic biochemical indexes in the control group was not obvious after treatment, and the improvement of metabolic biochemical indexes in the experimental group was significant after treatment, and the difference statistically significant(P<0.05).The patients in the experimental group were better than those in the control group after treatment, the difference was statistically significant(P<0.01).Conclusion Metformin combined with nutrition and exercise therapy can relieve the clinical signs of metabolic syndrome more effectively.The treatment is worthy of promotion in clinical practice.