Clinical study of continuous external drainage combined with intrathecal infusion of urokinase in prevention and treatment of cerebral vasospasm after aneurysm
10.3969/j.issn.1005-1678.2017.07.024
- VernacularTitle:脑脊液持续外引流联合鞘内注入尿激酶防治动脉瘤术后脑血管痉挛的临床研究
- Author:
Shengji YANG
;
Guangming XU
- Keywords:
continuous external drainage of cerebrospinal fluid;
intrathecal injection of urokinase;
cerebral vasospasm after aneurysm surgery;
clinical effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(7):66-67,70
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the persistent cerebrospinal fluid drainage and intrathecal injection of urokinase in prevention and treatment of cerebral vasospasm after aneurysm surgery.Methods The effect of prevention and treatment of cerebral vasospasm after aneurysm surgery in 40 patients, using the method combined with intrathecal injection of urine kinase for persistent cerebrospinal fluid drainage, and classified as the observation group;the other 40 cases patients with persistent cerebrospinal fluid drainage intervention, and classified as the control group, two groups of patients were in Shandong Provincial Hospital from January 2016 to January 2017.Results The incidence of rebleeding in two groups had no significant difference in observation of cerebral vasospasm in patients with the incidence was significantly lower than the control group, the observation The incidence of cerebral vasospasm group was 15.0%, 37.5% in the control group, compared two groups of patients with the prognosis, the obvious observation group of patients with good prognosis, comparison between groups showed significantly(P<0.05).Conclusion Persistent cerebrospinal fluid drainage and intrathecal injection of urokinase on the clinical study of postoperative cerebral vasospasm aneurysm found the simple, compared with continuous drainage of cerebrospinal fluid, can improve the clinical condition of patients, and promote the recovery of patients, reduce cerebral vascular spasm, so it is worthy of reference.
