Efficacy of statins combined with glucocorticoid in the treatment of primary nephrotic syndrome
10.3969/j.issn.1005-1678.2017.07.030
- VernacularTitle:他汀类药物联合糖皮质激素治疗原发性肾病综合征的疗效观察
- Author:
Shumin WANG
;
Jiebin YU
;
Xuexi HAO
;
Yanhua YANG
- Keywords:
primary nephrotic syndrome;
glucocorticoids;
statins;
renal function;
clinical efficacy
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(7):81-82,85
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study in primary nephrotic syndrome clinical effect in the treatment of statins combined with glucocorticoid for syndrome disease.Methods From May 2013 to February 2017 treatment of 90 cases of primary nephrotic syndrome patients as the research object, the patients were divided into control group and the application of the experimental group randomly, the control group received glucocorticoid therapy, the experimental group patients in the control group based on the addition of statin therapy, compared two groups of patients after treatment of triglyceride (TG), serum total cholesterol (TC), serum CRP, serum creatinine, two D dimer And 24 h urinary protein and clinical curative effect.Results After the treatment, the patients in the experimental group TG, TC, blood CRP, serum creatinine, two D dimer and 24 h urinary protein equivalents were significantly better than the control group (P<0.05);the clinical treatment of patients in the experimental group the total efficiency of 95.56% was significantly higher than that of the control group (73.33%), the difference was statistically significant(P<0.05).Conclusion Statins combined with glucocorticoids in the treatment of primary nephrotic syndrome can effectively improve serum albumin, reduce urinary protein content, promote the recovery of renal function, clinical curative effect, worth in clinical treatment.Line promotion application.
