Comparison of the efficacy of Doxofylline and aminophylline in the treatment of bronchial asthma

VernacularTitle:多索茶碱与氨茶碱治疗支气管哮喘患者疗效对比
Author: Haiqin WANG ; Dakui CAO ; Yangwei YAO
Keywords: doxofylline; aminophylline; bronchial asthma
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(7):164-165,167
CountryChina
Language:Chinese
Abstract: Objective To compare the clinical effect of Doxofylline and aminophylline in the treatment of bronchial asthma.Methods The clinical data of 112 patients with bronchial asthma treated in Jiaxing Second Hospital from February 2015 to December 2016 were retrospectively analyzed.The patients were divided into two groups: the treatment group(56 cases), the use of doxofylline treatment, and the control group(56 cases), the use of aminophylline treatment.After 1 w treatment, the curative effect and adverse reactions were compared between the two groups to observe the changes of lung function before and after treatment.Results The total effective rate of the treatment group and the control group were 91.07% and 76.79% respectively(P<0.05).After treatment, the FVC of the treatment group was(2.24±0.63)L, FEV1 was(1.59±0.47)L, VC was(2.94±0.77)L, the incidence of adverse reactions was 10.71%, which was superior to the control group, the difference was statistically significant(P<0.05).Conclusion Doxofylline treatment of bronchial asthma clinical efficacy is remarkable, worthy of clinical promotion.