Clinical effect of different doses of anthracyclines on breast cancer patients before chemotherapy

VernacularTitle:不同剂量蒽环类药物对乳腺癌术前化疗临床效果探讨
Author: Tuo LI ; Weimin WEN
Keywords: different doses; anthracycline; breast cancer; preoperative chemotherapy; clinical effect
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(7):194-195
CountryChina
Language:Chinese
Abstract: Objective To explore the effect of different doses of anthracycline on preoperative chemotherapy of breast cancer.Methods In 40 cases of breast cancer patients using small doses of anthracycline therapy, and classified as the control group, the other 40 patients using high-dose anthracycline therapy, and classified as observation group.Then observe two groups of patients were compared;the patients were in our hospital from January to December 2016 were treated.Results The total effective rate was 82.5% in the observation group and 62.5% in the control group, the difference between the two groups was statistically significant (P<0.05).The incidence of adverse reactions in the observation group was 0, the control group was 27.5%, and the incidence of adverse reactions in the two groups was statistically significant (P<0.05).Conclusion Different doses of anthracyclines on the clinical effect of chemotherapy before surgery for breast cancer research found that different the clinical effect of different doses produced by E100C and E75C, E100C can improve the treatment effect of the patients, and reduce the occurrence of toxicity, so it is worthy of reference.