Effect of low dose of dexamethasone combined with mannitol on early swelling of oral and maxillofacial injuries

VernacularTitle:小剂量的地塞米松药物与甘露醇合用对口腔颌面部损伤早期肿胀的疗效
Author: Ji LI ; Jun XIAO ; Jun XIONG
Keywords: small dose; dexamethasone drugs; mannitol; oral and maxillofacial injury; early swelling
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(7):202-203,206
CountryChina
Language:Chinese
Abstract: Objective To explore the effect of low dose of dexamethasone and mannitol on the early swelling of oral and maxillofacial injuries.Methods A total of 100 patients with oral and maxillofacial injuries who were treated in Huanggang City Center Hospital from February 2015 to January 2016 were divided into two groups by means of an envelope randomized group.Group 50 patients, group A patients received low doses of dexamethasone treatment, B group of patients on the basis of increased mannitol for treatment, compared the efficacy of both groups of patients with maxillofacial swelling improved.Results The clinical general improvement probability of group B was significantly higher than that of group A, and the distance between the horizontal direction and the vertical direction of group B was significantly higher than that of group A (P<0.05).Conclusion The combination of low dose dexamethasone and mannitol has a great effect on the early swelling of oral and maxillofacial injury, and it is worthy to be further implemented in the future clinical practice.