Research on the varieties, characteristics of new anti-HBV drugs and related clinical trials
10.3760/cma.j.issn.1674-2397.2017.03.001
- VernacularTitle:新研发抗HBV药物的品种、特性及临床研究
- Author:
Yilin MA
- Keywords:
Hepatitis B virus;
Anti-HBV drugs;
Therapies,investigational
- From:
Chinese Journal of Clinical Infectious Diseases
2017;10(3):161-169
- CountryChina
- Language:Chinese
-
Abstract:
HBV infection is a major public health threat around the world.At present, clinical anti-HBV drugs,including nucleoside/nucleotide analogues (NAs) and PegIFNα, can only directly or indirectly inhibit viral replication rather than viral elimination.In recent years, medical researchers and pharmaceutical enterprises are extensively researching and developing new drugs for treatment of HBV, and a variety of drugs have entered the stage of clinical trials.This article reviews the research progress on characteristics,safety and clinical trials,as well as the development trends of several currently available anti-HBV drugs, focusing on the target points and life cycle of HBV.
