A Case of Spontaneous Closure of Macular Hole in Infectious Posterior Uveitis Involving the Fovea.
10.3341/jkos.2016.57.1.155
- Author:
Min Woo KIM
1
;
Dong Yoon KIM
;
Yoon Jeon KIM
;
Soo Geun JOE
;
Joo Yong LEE
;
June Gone KIM
Author Information
1. Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. junekim@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Macular hole;
Posterior uveitis;
Spontaneous closure;
Toxocariasis
- MeSH:
Adult;
Albendazole;
Bone Marrow Transplantation;
Diagnosis;
Eosinophils;
Follow-Up Studies;
Humans;
Immunoglobulin E;
Immunoglobulin G;
Immunoglobulins;
Male;
Retinal Perforations*;
Retinaldehyde;
Tomography, Optical Coherence;
Toxocariasis;
Uveitis, Posterior*;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2016;57(1):155-160
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of macular hole secondary to presumptive infectious posterior uveitis involving the fovea that spontaneously resolved after medical treatment. CASE SUMMARY: A 33-year-old male visited our clinic for decreased visual acuity in his left eye. He was treated with immunosuppressive therapy including steroid after bone marrow transplantation. Best corrected visual acuity (BCVA) was 0.05 in the left eye. Slit lamp examination showed mild anterior vitritis, and fundus examination showed a macular hole with surrounding whitish infiltration at the fovea. Spectral domain optical coherence tomography (SD-OCT) revealed a full thickness macular hole with surrounding hyper-reflective masses with an infiltration-like appearance involving all retinal layers. Serum anti-toxocara IgG was positive (ELISA), and eosinophil count and immunoglobulin E was elevated. Under diagnosis of presumptive ocular toxocariasis, the patient was treated with albendazole. After medical treatment for toxocariasis, the whitish foveal infiltration became smaller and more discrete. SD-OCT revealed spontaneous closure of the macular hole, and BCVA was improved to 0.4 after a 4-month follow-up. CONCLUSIONS: We report a macular hole complicated by presumptive infectious posterior uveitis that experienced spontaneous closure after medical treatment for underlying infection.
