Clinical observation of low molecular weight heparin in different age points before and after femoral intertrochanteric fracture
10.3969/j.issn.1005-1678.2017.07.026
- VernacularTitle:低分子肝素在老年股骨粗隆间骨折手术前后不同时间点应用的临床观察
- Author:
Qianzhuang MIAO
- Keywords:
molecular heparin;
old femoral intertrochanteric fractures;
application at different time points;
clinical observation
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(7):71-72,75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical application of molecular heparin in the treatment of skeletal intertrochanteric fractures at different time points before and after operation.Methods The extraction time of 160 elderly patients with intertrochanteric fractures was divided into group A, group B, group C and group D according to the order of admission in our hospital from March 2015 to September 2016.Patients in group A were treated with molecular heparin at 48 h before surgery.Patients with group B were treated with molecular heparin 24 h before operation.Patients in group C were treated with molecular heparin at 12 h before surgery.Patients in group D were treated with molecular heparin at 12 h postoperatively.Results The incidence of DVT in the four groups was 2.5%, 15%, 15% and 37.5% respectively.The incidence of DVT in group A and group B, group C and group D was statistically significant.The statistical significance was significant(P< 0.05).The incidence of DVT in group B and group C was compared with that in group B.There was no statistically significant difference.1 month after surgery 4 groups of patients with lower extremity vascular color Doppler ultrasound review, there are 6 cases of new DVT patients, 3 months after surgery on the lower extremity vascular color Doppler ultrasound review of 2 cases of new patients, in addition to the four groups of patients with bleeding There was no statistically significant difference between the data.Conclusion The use of molecular heparin in the elderly patients with intertrochanteric fractures for 48 hours can effectively prevent the occurrence of DVT, and will not improve the incidence of hemorrhagic events and have high safety and reliability.
