Effect of TCM for removing blood stasis on promoting blood circulation and cerebral blood perfusion in patients with hypoperfusion/decreased embolic clearance type cerebral infarction
10.3969/j.issn.1005-1678.2017.07.043
- VernacularTitle:中药活血化瘀法对低灌注/栓子清除能力下降型脑梗死患者脑血流灌注量的影响
- Author:
Gao ZHENG
;
Yang ZHOU
;
Zhihua SHEN
- Keywords:
method for promoting blood circulation and removing blood stasis;
hypoperfusion;
cerebral infarction;
cerebral blood perfusion
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(7):114-115,118
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of breviscapine injection on cerebral blood perfusion in patients with hypoperfusion/decreased embolic clearance type cerebral infarction.Methods 100 patients with hypoperfusion/decreased embolic clearance type cerebral infarction in our hospital were selected and randomly divided into two groups.Both group were treated with conventional western medicines, and the experimental group was additionally treated with breviscapine injection.The plasma D-dimer (D-D), fibrinogen (Fib), systolic and diastolic blood pressure and recovery of neurological function were compared between the two groups.Results D-D and Fib levels and NIHSS score in the experimental group were significantly lower than those in the control group (P< 0.05), while the systolic blood pressure was significantly higher than that in the control group (P< 0.05).Conclusion Breviscapine injection can reduce the plasma D-D and Fib levels, increase cerebral vascular blood flow and improve the neurological function in patients with hypoperfusion/decreased embolic clearance type cerebral infarction.