The clinical efficacy and safety of nitroglycerin combined with atenolol in the treatment of coronary heart disease
10.3969/j.issn.1005-1678.2017.07.110
- VernacularTitle:硝酸甘油联合阿替洛尔治疗冠心病的临床疗效及安全性分析
- Author:
Yu LIU
- Keywords:
nitroglycerin;
atenolol;
clinical efficacy;
safety
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(7):271-273
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical efficacy and safety of nitroglycerin combined with atenolol in the treatment of coronary heart disease.Methods From February 2014 to November 2016, 114 cases of coronary heart disease patients treated in Zhongshan hospital were selected, all patients were randomly divided into experimental group and control group, the patients in experimental group were treated with nitroglycerin combined with atenolol, and the patients in control group were treated with nitroglycerin, the therapeutic effects of two groups were observed, the adverse reactions of the two groups were compared.Results After treatment, the total effective rate of the treatment group was 93% higher than that of the control group(78.9%), the difference was statistically significant(P< 0.05);The total effective rate of ECG in the experimental group was 89.5% higher than that in the control group(73.7%), the difference was statistically significant(P<0.05);There were 2 cases(3.5%)of adverse reactions in the experimental group and there were 11 cases(19.3%)of adverse reactions in the control group, which was significantly lower in the experimental group than that in the control group, the difference was statistically significant(P<0.05).Conclusion Phenyl bromide Malone and colchicine had good clinical curative effect in the treatment of chronic gout.
