Analysis on the risk factors of intracranial infection after neurosurgery and the therapeutic effect of vancomycin
10.3969/j.issn.1005-1678.2017.07.123
- VernacularTitle:神经外科术后颅内感染的危险因素分析及万古霉素的治疗效果研究
- Author:
Dandan ZHANG
;
Bin ZHOU
;
Hong ZHU
- Keywords:
neurosurgery;
craniotomy;
intracranial infection;
risk factors;
vancomycin
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(7):301-303
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of intracranial infection after neurosurgery and the effect of vancomycin.Methods 28 cases of craniotomy in this study, The First Hospital of Ningbo City from January 2011 to July 2014 during the years after the occurrence of intracranial infection patients as the research object, a retrospective analysis of the age, gender, emergency, basic diseases, mastoid airroom, ventricle drainage, posterior fossa surgery, reoperation and operation time (more than 4h).The clinical data, summarize the risk factors of postoperative intracranial infection in department of neurosurgery and to observe the clinical effect of vancomycin in the treatment of such patients.Result The high risk factors of intracranial infection include: Open mastoid gas room during operation, ireoperation, ventricular drainage and operative time (more than 4h).In 28 cases with intracranial infection after craniotomy, the total effective rate of vancomycin treatment was 100.00%.Conclusion The high risk factors of intracranial infection after operation include open surgery, mastoid room, reoperation, ventricular drainage and longer operation time.Vancomycin is an effective drug in the treatment of intracranial infection in the department of neurosurgery.