Experimental Toxocara cati Infection in Gerbils and Rats.
10.3347/kjp.2010.48.4.331
- Author:
Mohammad ZIBAEI
1
;
Seyed Mahmoud SADJJADI
;
Shoji UGA
Author Information
1. Department of Parasitology and Mycology, School of Medicine, Lorestan University of Medical Sciences, Khorram Abad, Iran. zibaeim@sums.ac.ir
- Publication Type:Brief Communication
- Keywords:
Toxocara cati;
Mongolian gerbil;
Wistar rat;
experimental infection
- MeSH:
Animal Structures/parasitology;
Animals;
*Disease Models, Animal;
Gerbillinae;
Histocytochemistry;
Male;
Microscopy;
Rats;
Rats, Wistar;
Toxocara/*pathogenicity;
Toxocariasis/*parasitology/*pathology
- From:The Korean Journal of Parasitology
2010;48(4):331-333
- CountryRepublic of Korea
- Language:English
-
Abstract:
Mongolian gerbils and Wistar rats were inoculated orally with 240 and 2,500 Toxocara cati embryonated eggs, respectively, to evaluate the larval recovery in different tissues and organs, such as the liver, lungs, heart, kidney, and skeletal muscles after 5, 30, 49, 70, and 92 days post-infection (PI). Larval recovery rates were 1.7-30.0% in Mongolian gerbils on days 5-92 PI and 0.2-3.8% in rats on the same days. These results indicate that Mongolian gerbils and Wistar rats are suitable experimental paratenic hosts for the study of neurological toxocariasis as well as visceral toxocariasis.
