Clinical research of humidified high flow nasal cannula for bronchitis in children
10.3760/cma.j.issn.1673-4912.2017.06.007
- VernacularTitle:加温湿化高流量鼻导管吸氧治疗儿童毛细支气管炎的临床研究
- Author:
Xinli YANG
;
Liyun CUI
;
Qing MI
;
Baohai SHI
;
Liping CHEN
- Keywords:
Humidified high flow nasal cannula;
Bronchiolitis
- From:
Chinese Pediatric Emergency Medicine
2017;24(6):430-433
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical application value of humidified high flow nasal cannula(HHFNC) on bronchitis in children.Methods Total 85 cases of bronchitis that needed oxygen therapy in our department from Oct 2015 to Feb 2016 were randomly divided into three groups,HHFNC group,NCPAP group and nasal cannula oxygen group(control group).According to the blood gas results,FiO2 was adjusted to maintain PaO2 in 50~70mmHg(1mmHg=0.133kPa),TcSO2 90% to 95%.The main symptoms and signs(wheezing,shortness of breath,three depression sign,wheezing rale) disappeared time,length of oxygen inhalation and stay,the change of PaO2,PaCO2,respiratory rate were compared among the three groups.Results Compared with control group,the clinical symptoms and signs disappeared time and length of oxygen inhalation and stay were significantly shorter in HHFNC group(P<0.05).The recovery of blood gas and respiratory rate in HHFNC group were better than those in control group(P<0.05).No statistically significant differences existed between HHFNC group and NCPAP group(P>0.05).Conclusion HHFNC can significantly improve the clinical symptoms,signs and blood gas results in children with bronchitis,reduce the length of oxygen inhalation and stay.HHFNC is an effective and well-tolerated treatment for bronchitis in children.
