Research advances in gold nanoparticle-mediated tumor radiosensitization

VernacularTitle:金纳米颗粒在肿瘤放射增敏中的相关研究进展
Author: Ning ZHAO ; Shen FU
Keywords: Gold nanoparticles; Physical properties; Radiosensitization; Clinical application
From: Chinese Journal of Radiation Oncology 2017;26(7):838-841
CountryChina
Language:Chinese
Abstract: Nanotechnology has been extensively applied in the diagnosis and treatment of cancer, and is currently a major focus of research worldwide.Among the various nanomaterials, gold nanoparticles (GNPs) are of particular interest to many researchers due to their superior properties of low cytotoxicity, good biocompatibility, and preferential accumulation in tumors (the enhanced permeability and retention effect), which in turn gives GNPs a potential application in cancer diagnostics, imaging, photothermal therapy, and radiotherapy.Many published studies have shown that GNPs can be used as a new ideal radiosensitizer, and therefore understanding the radiosensitizing effects of GNPs both in vitro and in vivo will be of great significance in the clinical translation of nanomedicine.