PET reporter gene imaging in cellular immunotherapy for cancer
10.3760/cma.j.issn.2095-2848.2017.07.011
- VernacularTitle:PET报告基因显像监测肿瘤细胞免疫治疗的进展
- Author:
Xiaofeng LI
;
Wengui XU
- Keywords:
Neoplasms;
Immunotherapy;
Positron-emission tomography;
Genes;
reporter
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2017;37(7):426-429
- CountryChina
- Language:Chinese
-
Abstract:
As an important in vivo noninvasive molecular imaging modality, PET imaging can quantify and visualize the serial trafficking, tumor targeting, cell number maintenance, cell expansion, activation and immunological function of adoptive immune cells in cancer cell therapy. Thereby it may play a significant role in the treatment options and efficacy evaluation for cellular immunotherapy in cancer. This review focuses on PET reporter gene imaging which has been studied intensively and applied widely in the research on imaging monitoring of cellular immunotherapy for cancer, with the purpose to provide innovative clues for the preclinical study and clinical translation research.
