The study of re-irradiation for head and neck cancer
10.3760/cma.j.issn.1004-4221.2017.07.001
- VernacularTitle:复发头颈部癌再程放疗研究
- Author:
Xuegua LU
;
Chaosu HU
- Keywords:
Neoplasm recurrence;
head and neck;
Re-irradiation
- From:
Chinese Journal of Radiation Oncology
2017;26(7):723-727
- CountryChina
- Language:Chinese
-
Abstract:
Nearly 50% patients with head and neck cancer after radiotherapy will recurrence in the previous radiation fields.Salvage surgery is the first choice of treatment.Clinical studies have shown that a small number of patients with recurrent head and neck cancer can benefit from salvage surgery plus postoperative re-irradiation or re-irradiation with or without chemotherapy or targeted therapy,and these patients can achieved tumor control and long-term survival.However, the overall efficacy is not satisfactory, and often accompanied by severe acute and late, and even fatal treatment-related toxicity.Therefore, it is necessary to give full consideration to the condition of recurrent tumor, the first radiotherapy related factors and the patient′s related status before implementation of re-irradiation.The development of radiotherapy technology and comprehensive treatment, including the clinical application of proton and heavy ion and immune therapy, provides the possibility of improving the prognosis and reducing treatment-related toxicity for these patients.
