Study on purification, concentration and drying technic of Fushubao gel
10.3760/cma.j.issn.1673-4246.2017.07.011
- VernacularTitle:妇舒保凝胶精制、浓缩及干燥工艺研究
- Author:
Yuechan ZHANG
;
Jianchun WANG
;
Rui YANG
- Keywords:
Pharmaceutical Technology (TCD);
Fushubao gel;
Purification technology;
Concentration technology;
Desiccation
- From:
International Journal of Traditional Chinese Medicine
2017;39(7):622-628
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the purification, concentration and drying technology of Fushubao gel. Methods The purification technology of Fushubao gel was optimizing by the total retention rate of Rhein, emodin, physcion and purity of content. The concentration, drying technology of Fushubao gel was optimized by the transfering rate of Rhein, emodin, physcion and Berberine hydrochloride. Results Best refining technology included in the condition of the water extract of 0.2 g/ml at 70 ℃, the ZTC1+1-II clarifying agent B 0.6 ml/g was mixed10 min in a 70 ℃ water bath thermal insulation 30 min; And then agent A 0.3 ml/g was added and mixed 10 min in a 70 water bath thermal insulation 30 min; after 12 h, filter it. Best thickening, drying technology was in the vacuum for -0.08~-0.09 MPa, a temperature of 60 ℃, the pressure was reduced to concentrate its relative density about 1.05 and concentrated liquid spray was dryed. Conclusions The purification, concentration and drying technology of Fushubao gel is reasonable, and can be used in the production.
