Efficacy and safety of budesonide turbuhaler in Korean asthmatic patients.
- Author:
You Young KIM
;
Sang Heon CHO
;
Kyung Up MIN
- Publication Type:Original Article ; Randomized Controlled Trial
- MeSH:
Asthma;
Budesonide*;
Cough;
Dyspnea;
Humans;
Inhalation;
Peak Expiratory Flow Rate;
Respiratory Sounds;
Terbutaline;
Thorax
- From:Korean Journal of Allergy
1997;17(1):49-57
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A controlled study was carried out in 50 patients with perennial bronchial asthma to assess the efficacy and safety of budesonide turbuhaler. Subjects have suffered from cough, wheezing, dyspnea and chest tightness and showed either 15% of reversibility in FEV after bronchodilator inhalation or airway hyperresponsiveness to methacholine(PC20 < or = 25mg/ml.) Patients were randomized to treatment with budesonide turbuhaler or terbutaline turbuhaler for 8 weeks after 2 weeks of run-in period. Budesonide turbuhaler was effective for cough, wheezing, dyspnea and chest tightness. It improved peak expiratory flow rate and FEV1. Budesonide turbuhaler was tolerated well and the laboratory tests showed no abnormality. It is suggested that budesonide turbuhaler is effective and safe in the management of bronchial asthma.
