Effects of transcranial magnetic stimulation on the cognitive ability of patients with cognitive impairment after cerebral venous thrombosis
10.3760/cma.j.issn.0254-1424.2017.05.002
- VernacularTitle:重复经颅磁刺激对脑静脉血栓形成后认知功能障碍的影响
- Author:
Gang LI
;
Liuyi LI
;
Jia SONG
;
Mi PANG
;
Mingming MA
;
Changshui XU
;
Jiewen ZHANG
- Keywords:
Transcranial magnetic stimulation;
Cerebral venous thrombosis;
Cognitive impairment;
Event-related potentials
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2017;39(5):327-331
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore any effect of repetitive transcranial magnetic stimulation (rTMS) on the cognitive ability of patients suffering from cognitive impairment after cerebral venous thrombosis (CVT).Methods Forty-three CVT patients with cognitive impairment were recruited and randomly assigned into an rTMS group (n =23) or a control group (n=20).Both groups received routine drug therapy and cognitive function training,while the rTMS group was additionally given rTMS.The treatment lasted 4 weeks.The Montreal cognitive assessment (MoCA),the Hamilton depression scale (HAMD),the modified auditory Barthel Index (MBI) and event-related potential P300 were used to test both groups before and after the treatment.Results After the treatment the average MoCA and MBI scores of both groups had increased significantly,while their average HAMD scores had decreased significantly compared to before the treatment.For both groups,the P300 latency had shortened significantly and the amplitude increased significantly after the treatment.The improvement in all of these indicators was significantly greater in the rTMS group than in the control group.Conclusion Supplementing drug therapy with rTMS can significantly improve the cognitive ability of CVT patients and is worth applying in clinical practice.
