Clinical significance of MR-guided prostate biopsy based on diffusion-weighted imaging abnormalities for prostate cancer diagnosis in elderly men
10.3760/cma.j.issn.0254-9026.2017.06.017
- VernacularTitle:扩散加权成像异常的磁共振引导前列腺穿刺活检对老年前列腺癌患者的诊断价值
- Author:
Tao GU
;
Jingying YU
;
Chunmei LI
;
Xiaotao DENG
;
Zhipeng ZHANG
;
Tan GUO
;
Jingtao ZHANG
;
Hong WANG
;
Min CHEN
;
Jianye WANG
- Keywords:
Magnetic resonance Imaging;
Punctures;
Prostatic neoplasms
- From:
Chinese Journal of Geriatrics
2017;36(6):673-676
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic efficacy of magnetic resonance(MR)-guided prostate biopsy based on abnormal diffusion weighted imaging for prostate cancer in elder men.Methods From July 2014 to Dec 2016,56 patients (age≥ 65 years) with diffusion weighted imaging (DWI)abnormalities undergoing MR-guided prostate biopsy were retrospectively evaluated.According to pathological diagnosis,patients were divided into prostate cancer and non-prostate cancer groups.The clinical data of two groups were analyzed.The correlation of Gleason score,prostate specific antigen(PSA),and the location and number of biopsy were compared.Results Among 56 cases,32 (57.1％)were diagnosed as prostate cancer,and 24 (42.9％)as chronic prostatitis and prostatic hyperplasia (non-prostate cancer).There were statistically significant differences between prostate cancer and non-prostate cancer in age[(73.0±5.7)vs.(70.1±4.3)year]and PSA[(9.3±6.0)μg/L vs.(6.0± 3.9)μg/L] (both P＜0.05),and no statistical differences in biopsy location and biopsy number(t =2.08,2.37,P＞ 0.05).Gleason score had no correlation with PSA level and biopsy location and biopsy number(r=0.189、-0.183、0.082,P＞0.05).Conclusions MR-guided prostate biopsy based on MR-DWI has some merits,such as accurate positioning,fewer numbers of biopsy,and lower false-negative rate.
