Advances in Study on SEPT9 Gene Methylation in Diagnosis of Colorectal Cancer
10.3969/j.issn.1008-7125.2017.06.013
- VernacularTitle:SEPT9基因甲基化在结直肠癌诊断中的研究进展
- Author:
Lei WEN
;
Yichao FENG
;
Xia DU
- Keywords:
Colorectal Neoplasms;
SEPT9 Gene;
Methylation;
Diagnosis
- From:
Chinese Journal of Gastroenterology
2017;22(6):381-384
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies with poor prognosis and high mortality.SEPT9 gene is a tumor suppressor gene and plays an important role in the end of cell division.Studies have shown that methylation of SEPT9 gene could be used in the early diagnosis of CRC.This article reviewed the advances in study on SEPT9 gene methylation in the screening and diagnosis of CRC.