Survival analysis of unresectable advanced pancreatic cancer after high intensity focused ultrasound therapy
10.3969/j.issn.1671-8348.2017.16.009
- VernacularTitle:无法手术的中晚期胰腺癌HIFU治疗后的生存分析
- Author:
Zhe ZHANG
;
Chengbing JIN
;
Kun ZHOU
;
Lifeng RAN
;
Wei YANG
- Keywords:
high intensity focused ultrasound;
advanced pancreatic cancer;
survival analysis
- From:
Chongqing Medicine
2017;46(16):2190-2192
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the 2-year survival situation of high intensity focused ultrasound(HIFU) treatment in unr esectable advanced pancreatic carcinoma.Methods Thirty-eight patients with unresectable pancreatic cancer received HIFU treatment.After treatment,the changes of laboratory tumor markers examination results,pain score,life quality score and survival situation were recorded.Results Among 35 patients with pain symptom before HIFU treatment,pain was relieved after HIFU treatment in 28 cases,the remission rate was 80.0％.The CA19-9 and CEA levels after HIFU therapy were obviously reduced compared with before treatment.The imaging examination showed the coagulation necrosis in HIFU-treated area.It was found the tumor volume was obviously shrunk during follow-up period.The median survival period was extended to (12.9 ± 6.6) months.Conclusion The HIFU treatment can effectively improve the life quality in the patients with unresectable pancreatic cancer and extends their survival period.
