A meta-analysis on smoking and pulmonary tuberculosis incidence in Chinese people

VernacularTitle:吸烟与中国人群肺结核发病的Meta分析
Author: Jia WEI ; Li PENG ; Hong CHEN
Keywords: pulmonary tuberculosis; risk factors; smoking; meta analysis
From: Chongqing Medicine 2017;46(16):2224-2227,2232
CountryChina
Language:Chinese
Abstract: Objective To study the relationship between smoking and the incidence of pulmonary tuberculosis(TB) in Chinese people.Methods The Pubmed database and three Chinese databases such as Wanfang Data,Veipu data(VIP) and China national knowledge infrastructure database (CNKI) were retrieved.The literatures on the relationship between smoking and pulmonary TB incidence in Chinese people published before April 2016 were analyzed.Results Fifteen studies were included,after excluding 1 low quality study,the rest had no statistical heterogeneity.The merged odd ratio (OR) was 1.71,95 ％ confidence interval (CI) 1.51-1.90.Two studies observed the relationship between the amount of cigarettes and TB pathogenesis,but there was heterogeneity and could not be further merged the OR value for conducting analysis.No subgroup analysis of gender was performed in all studies.Conclusion The risk suffering from pulmonary TB in Chinese smokers is 1.71 fold of non-smokers,and smoking increases the risk of pulmonary TB onset.