Establishment and comparison of right ventricular failure of animal models
10.3969.j.issn.1671-7856.2017.06.019
- VernacularTitle:右心衰竭动物模型的建立和比较
- Author:
Yujie WANG
;
Xiangrong ZUO
- Keywords:
Right ventricular failure;
Pulmonary arterial hypertension;
Animal models;
Modeling;
Comparison
- From:
Chinese Journal of Comparative Medicine
2017;27(6):92-97
- CountryChina
- Language:Chinese
-
Abstract:
Right ventricular failure(RVF)is a severe clinical syndrome that affects human health seriously.The establishment and application of experimental animal models are critical to research the pathogenesis, pathophysiology, prevention and treatment of RVF.Recently, numerous researchers have studied the modeling methods and testing indexes of RVF of animal models, which has improved the success rate and quality of the models.However, even if so many models, there is still no widely accepted experimental animal model of RVF because of the different and complex modeling methods, material selection and experimental conditions.This article reviews the methods and mechanism of multiple experimental animal models of RVF and compares them, so as to provide reference for choosing and applying experimental animal models of RVF in the study.
