Risk factors in elderly thermal burn patients with acute ischemic stroke
10.3969/j.issn.1009-0126.2017.06.015
- VernacularTitle:老年热烧伤患者并发急性脑梗死的危险因素分析
- Author:
Lingling XU
;
Xin WANG
;
Bin ZHANG
- Keywords:
burns;
brain infarction;
fibrinogen;
tumor necrosis factor-alpha;
interleukin-6
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2017;19(6):611-614
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the risk factors in elderly moderate-severe thermal burn patients with acute ischemic stroke (AIS).Methods Forty-two elderly moderate-severe thermal burn patients with AIS served as an observation group and 47 elderly moderate-severe thermal burn patients without AIS served as a control group in this study.Risk factors in thermal burn patients with AIS were analyzed by univariate and multivariate logistic regression analysis respectively.Results The number of neutrophils and platelets,hematocrit,serum levels of fibrinogen,thromboxane A2,creatinine,procalcitonin,C-reactive protein,TNF-α and interleukin-6 (IL-6) were significantly higher while the systolic blood pressure (SBP) on admission was significantly lower in observation group than in control group (P＜0.01).Logistic regression analysis showed that SBP on admission,serum levels of fibrinogen,thromboxane A2,TNF-α and IL-6 were the independent risk factors in elderly moderate-severe thermal burn patients with AIS (OR =1.106,95％CI:1.007-1.501,P=0.007;OR=3.316,95 ％ CI:1.251-8.792,P=0.016;OR=1.077,95％CI:1.003-1.156,P=0.041;OR=2.901,95％CI:1.109-2.799,P=0.013;OR=1.502,95％CI:1.581-2.031,P=0.021).Conclusion SBP on admission,serum levels of fibrinogen,thromboxane A2,TNF-α and IL-6 are the independent risk factors in elderly moderate-severe thermal burn patients with AIS.
