Assessment of the Asian Neurogastroenterology and Motility Association Chronic Constipation Criteria: An Asian Multicenter Cross-sectional Study.
- Author:
Kok Ann GWEE
1
;
Paul BERGMANS
;
JinYong KIM
;
Bogdana COUDSY
;
Angelia SIM
;
Minhu CHEN
;
Lin LIN
;
Xiaohua HOU
;
Huahong WANG
;
Khean Lee GOH
;
John A PANGILINAN
;
Nayoung KIM
;
Stanislas Bruley DES VARANNES
Author Information
- Publication Type:Multicenter Study ; Original Article
- Keywords: Asia; Constipation; Cross-sectional studies; Humans; Practice guidelines as topic/standards
- MeSH: Asia; Asian Continental Ancestry Group*; Constipation*; Cross-Sectional Studies*; Diagnosis; Humans; Judgment; Outpatients
- From:Journal of Neurogastroenterology and Motility 2017;23(2):262-272
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: There is a need for a simple and practical tool adapted for the diagnosis of chronic constipation (CC) in the Asian population. This study compared the Asian Neurogastroenterology and Motility Association (ANMA) CC tool and Rome III criteria for the diagnosis of CC in Asian subjects. METHODS: This multicenter, cross-sectional study included subjects presenting at outpatient gastrointestinal clinics across Asia. Subjects with CC alert symptoms completed a combination Diagnosis Questionnaire to obtain a diagnosis based on 4 different diagnostic methods: self-defined, investigator's judgment, ANMA CC tool, and Rome III criteria. The primary endpoint was the level of agreement/disagreement between the ANMA CC diagnostic tool and Rome III criteria for the diagnosis of CC. RESULTS: The primary analysis comprised of 449 subjects, 414 of whom had a positive diagnosis according to the ANMA CC tool. Rome III positive/ANMA positive and Rome III negative/ANMA negative diagnoses were reported in 76.8% and 7.8% of subjects, respectively, resulting in an overall percentage agreement of 84.6% between the 2 diagnostic methods. The overall percentage disagreement between these 2 diagnostic methods was 15.4%. A higher level of agreement was seen between the ANMA CC tool and self-defined (374 subjects [90.3%]) or investigator’s judgment criteria (388 subjects [93.7%]) compared with the Rome III criteria. CONCLUSION: This study demonstrates that the ANMA CC tool can be a useful for Asian patients with CC.
