Feasibility of quantitative assessment of pancreatic perfusion with dynamic contrast-enhanced MRI in healthy volunteers
10.13929/j.1003-3289.201609129
- VernacularTitle:动态增强磁共振成像定量评估健康志愿者胰腺灌注的可行性
- Author:
Weiwei ZHAO
;
Jing REN
;
Hong YIN
;
Yi HUAN
- Keywords:
Pancreas;
Perfusion imaging;
Magnetic resonance imaging;
Contrast media;
Quantitative parameters
- From:
Chinese Journal of Medical Imaging Technology
2017;33(6):893-896
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility of quantitative assessment of pancreatic perfusion using dynamic contrastenhanced MRI (DCE-MRI).Methods Totally 68 healthy volunteers were divided into youth,middle and old groups according to ages.All volunteers underwent pancreas DCE-MRI examination.Images were transmitted to Research-DCE MRI Tool workstation to calculate the quantitative parameters,including volume transfer constant (Ktrans),interstitium-toplasma rate constant (Kep),interstitial volume (Ve) and plasma volume (Vp).Independent sample t test and one-way ANOVA test were used to evaluate the differences of pancreatic perfusion.Results There were no significant differences of Ktrans,Kep, Ve and Vp between male and female;Ve in old group was higher than that in youth and middle groups (P =0.036,0.001);Vp of pancreatic head was higher than that of pancreatic body and tail (P=0.011,0.023).Conclusion DCE-MRI can be applied to provide a reliable quantitative assessment of pancreatic perfusion noninvasively.The parameters of DCE-MRI of pancreatic perfusion are independent of gender but vary with age and pancreatic sites.
