Development of bio-genomics database for major disease clinical samples based on specific disease cohort
10.3969/j.issn.1671-3982.2017.06.003
- VernacularTitle:基于专病队列的重大疾病临床样本生命组学数据库建设
- Author:
Wei LI
;
Shiquan WANG
- Keywords:
Genome;
Clinical phenotype;
Integration;
Precision medicine;
Bio-genomics;
Data sharing;
Data quality
- From:Chinese Journal of Medical Library and Information Science
2017;26(6):11-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the nation-wide cooperation network of bio-genomics for major disease clinical samples and the development of bio-genomics database.Methods The clinical phenotypes and genomics data of disease cohort were investigated,the cooperation network of bio-genomics for major disease clinical samples and the development of bio-genomics database were analyzed,the key technologies for different tasks were studied.Results The key contents and technologies involving the development of bio-genomics database for major disease clinical samples were proposed and how to solve the following problems was pointed out,including the integration of phenotypes and new technologies in the genomics field,multi-granular and multi-modular retrieval,and computing service.Conclusion It is of great importance to establish the standards for data cooperation process and data security management,to research and develop platform for cooperation network and database,to study the service model for the integration of big data in precision medicine based on data cooperation network.
