Effect of Tongxinluo on carotid artery stenosisthe,hs-CRP and D-Dimer in patients with cerebral infarction
10.3969/j.issn.1673-4130.2017.12.003
- VernacularTitle:通心络治疗对脑梗死患者颈动脉狭窄程度和超敏C反应蛋白及D-二聚体水平的影响
- Author:
Guoqing MI
;
Manzhong XUE
;
Yu FU
;
Hongying MA
;
Li LI
;
Lianhui WANG
- Keywords:
Tongxinluo;
cerebral infarction;
high sensitivity C reactive protein;
D-Dimer
- From:
International Journal of Laboratory Medicine
2017;38(12):1591-1593
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Tongxinluo on carotid artery stenosis,and the levels of high sensitive C reactive protein(hs-CRP) and D-Dimer in patients with cerebral infarction.Methods 168 patients with cerebral infarction treated in this hospital from June 2014 to June 2015 were randomly divided into experimental group and control group,with 84 cases in each group.The patients in both group received routine treatment.In addition to that,patients in the experimental group also used Tongxinluo capsule for 6 months as a course of treatment.After a course of treatment,Doppler ultrasound diagnosis instrument was used to detect carotid arterial intima-media thickness,plaque area and carotid artery stenosis rate.Hs-CRP and D-Dimer levels were also detected.Results After treatment,the carotid arterial intima-media thickness,plaque area and carotid vascular stenosis rate in two group were significantly decreased(P<0.05),but the three indicators in experimental group were decreased more significantly(P<0.05).After a course of treatment,the levels of D-Dimer and hs-CRP in peripheral blood of the two groups were significantly decreased(P<0.05),but the content of D-Dimer and hs-CRP was much lower in the experimental group(P<0.05).Conclusion Tongxinluo treatment could effectively reduce the level of hs-CRP and D-Dimer in patients with cerebral infarction,and alleviate the carotid artery stenosis,which might be worthy of clinical application.
